Publications
Drosophila FMRP recruits the miRISC to target mRNAs to repress translation
Kaul N, Pradhan SJ, Boin NG, Mason MM, Rosales J, Starke EL, Wilikinson EC, Chapman EG, Barbee SA. Biorxiv, 2023. Biorxiv
Identification of RNA Fragments Resulting from Enzymatic Digestion using MALDI-TOF Mass Spectrometry
Schowe SW, Langeberg CL, Chapman EG, Brown K, Resendiz MJE. Journal of Visual Experiments, 2022. pubmed
Processing of RNA Containing 8-Oxo-7,8-Dihydroguanosine (8-oxoG) by the Exoribonuclease Xrn-1
Phillips CN, Schowe S, Langeberg CJ, Siddique, Chapman EG, Resendiz MJE. Front. Mol. Biosciences, 2021. pubmed
Custom-designed, degradation-resistant messenger RNAs in yeast
Franklin AL, Macfadden A, Kieft JS, Hesselberth JR, Chapman EG. Biorxiv, 2020. biorxiv
Biochemical characterization of yeast XRN1
Langeberg CJ, Welch WRW, McGuire JV, Ashby A, Jackson AD, and Chapman EG. Biochemistry, 2020. pubmed
From EGC as a graduate student and postdoc:
Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs
MacFadden A, O'Donoghue Z, Silva PAGC, Chapman EG, Olsthoorn RC, Sterken MG, Pijlman GP, Bredenbeek PJ, Kieft JS. Nature Communications, 2018. pubmed
New hypotheses derived from the structure of a flaviviral Xrn1-resistant RNA: Conservation, folding, and host adaptation
Kieft JS, Rabe JL, Chapman EG. RNA Biology, 2015. pubmed
The structural basis of pathogenic subgenomic flavivirus RNA (sfRNA) production
Chapman EG, Costantino DA, Rabe JL, Moon SL, Wilusz J, Nix JC, Kieft JS. Science, 2014. pubmed
RNA structures that resist degradation by Xrn1 produce a pathogenic Dengue virus RNA
Chapman EG, Moon SL, Wilusz J, Kieft JS. Elife, 2014. pubmed
Site-specific platinum(II) cross-linking in a ribozyme active site
Chapman EG, DeRose VJ. Journal of the American Chemical Society, 2012. pubmed
Binding of kinetically inert metal ions to RNA: the case of platinum(II)
Chapman EG, Hostetter AA, Osborn MF, Miller AL, DeRose VJ. Metal Ions in Life Sciences, 2011. pubmed
Enzymatic processing of platinated RNAs
Chapman EG, DeRose VJ. Journal of the American Chemical Society, 2010. pubmed
Rapid cross-linking of an RNA internal loop by the anticancer drug cisplatin
Hostetter AA, Chapman EG, DeRose VJ. Journal of the American Chemical Society, 2009. pubmed