Publications

Custom-designed, degradation-resistant messenger RNAs in yeast

Franklin AL, Macfadden A, Kieft JS, Hesselberth JR, Chapman EG. Biorxiv, 2020. biorxiv


Biochemical characterization of yeast XRN1

Langeberg CJ, Welch WRW, McGuire JV, Ashby A, Jackson AD, and Chapman EG. Biochemistry, 2020. pubmed



From EGC as a graduate student and postdoc:


Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs

MacFadden A, O'Donoghue Z, Silva PAGC, Chapman EG, Olsthoorn RC, Sterken MG, Pijlman GP, Bredenbeek PJ, Kieft JS. Nature Communications, 2018. pubmed


New hypotheses derived from the structure of a flaviviral Xrn1-resistant RNA: Conservation, folding, and host adaptation

Kieft JS, Rabe JL, Chapman EG. RNA Biology, 2015. pubmed


The structural basis of pathogenic subgenomic flavivirus RNA (sfRNA) production

Chapman EG, Costantino DA, Rabe JL, Moon SL, Wilusz J, Nix JC, Kieft JS. Science, 2014. pubmed


RNA structures that resist degradation by Xrn1 produce a pathogenic Dengue virus RNA

Chapman EG, Moon SL, Wilusz J, Kieft JS. Elife, 2014. pubmed


Site-specific platinum(II) cross-linking in a ribozyme active site

Chapman EG, DeRose VJ. Journal of the American Chem Society, 2012. pubmed


Binding of kinetically inert metal ions to RNA: the case of platinum(II)

Chapman EG, Hostetter AA, Osborn MF, Miller AL, DeRose VJ. Metal Ions in Life Sciences, 2011. pubmed


Enzymatic processing of platinated RNAs

Chapman EG, DeRose VJ. Journal of the American Chem Society, 2010. pubmed


Rapid cross-linking of an RNA internal loop by the anticancer drug cisplatin

Hostetter AA, Chapman EG, DeRose VJ. Journal of the American Chem Society, 2009. pubmed